Intraoperative irradiation Therapy for Curatively Resected Rectal Cancer

Takashi Noto, Masami Ikeda, Seiei Yasuda, Tomoo Tajima, Toshio Mitomi, Tetsuji Sasaki¹⁾, Tomoyuki Mori²⁾

Second Department of Surgery, Tokai University School of Medicine
1) Department of Surgery, Tokai University Tokyo Hospital
2) Department of Radiation Oncology, Tokai University School of Medicine

Eighteen patients who had curatively resected rectal cancer have received intraoperative radiation therapy. The operations comprises 11 Miles'operations, 5 sphincter-saving operations and 2 pelvic exenterations. Lymphnode metastases were seen in 7 cases. Four cases showed direct invasion into the adjacent organs without lymphnode metastases. The radiation doses were 30∼40 Gy with the energy of 6∼18 MeV. Although the survival rate has not improved so far, the local recurrence rate has decreased. In regard to the safety of the operation, prolongation of operating time was apparent, though the total amount of blood lost and post operative changes in serum albumin levels and total lymphocyte counts were not different from those of control groups. There was a late complication, in one case: ureter stenosis, which could be dilated with a nephrostomy tube.

Key words
intraoperative irradiation, radiotherapy for rectal cancer, rectal cancer

Reprint requests
Takashi Noto Department of Surgery II, School of Medicine, Tokai University
Bouseidai, Isehara, 259-11 JAPAN

Accepted
June 13, 1990

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