Medullary Carcinoma with Lymphoid Infiltration of Esophagus, Report of a Case

Kyouichi Mizutani, Hiroyasu Makuuchi, Takao Machimura, Takashi Sugihara, Yoshio Sou, Hideo Shimada, Kouji Kanno, Hitoshi Hanaue, Tetsuji Sasaki, Tomoo Tajima, Toshio Mitomi

Second Department of Surgery, Tokai University School of Medicine

A very rare case of a poorly differentiated squamous cell carcinoma of the esophagus with medullary carcinoma with lymphoid infiltration in a 65-year-old woman is described. The radiograph of the esophagus showed a serrated lesion from the middle to the inferior thoracic esophagus. Endoscopic examination of the esophagus showed a tumor of Borrmann 2 type similar to a submucosal tumor. The surgical specimen showed an ulcerative tumor, similar to a submucosal tumor, measuring 4.7×3.2 cm. Most of the tumor was positively stained with Lugol's solution. High power microscopic observation revealed medullary carcinoma with marked lymphoid infiltration predominantly of T-cells. This case, as well as medullary carcinoma with lymphoid infiltration of brest cancer and gastric cancer and "blue cell cancer" had a good outcome. This is the first report which describes medullary carcinoma with lymphoid infiltration of esophageal cancer in Japan.

Key words
esophageal cancer, medullary carcinoma with lymphoid infiltration, blue cell cancer

Reprint requests
Kyouichi Mizutani Department of Surgery, Hamaoka Municipal Hospital
2060 Ikeshinden, Hamaoka-cho, Ogasa-gun, Shizuoka, 437 JAPAN

Accepted
November 19, 1990

To read the PDF file you will need Abobe Reader installed on your computer.