ORIGINAL ARTICLE
A Trial of Estimation of Invasion Depth in Early Gastric Cancer by Discriminant Analysis
Eiji Kanehira, Masaaki Nakagawa*, Yukimitsu Kawaura, Kenji Omura**, Hiroshi Hikishima**, Ichiro Nakano
The Department of Surgery, Saiseikai Ishikawa General Hospital
*The Department of General Surgery, Ishikawa Prefectural Central Hospital
**The Department of Surgery (1), Kanazawa University School of Medicine
A total of 258 solitary early gastric cancers (149 m-cancers, 109 sm-cancers) were statistically analyzed to estimate the depth of invasion. The influence of seven objective variables was assessed by discriminant analysis to obtain the following discriminant function: Z (x) =-3.44×10-1x1-8.08×10-1x2+2.08x3-6.79×10-1x4+6.49×10-1x5+5.62×10-1x6-2.15 (x1, x2, x3, x4, x5, and x6 are maximum diameter, gross appearance, location-1, histological type, location-2, and sex respectively). The accuracy of this estimation was 73.8% for m-cancer and 64.2% for sm-cancer. The incidence of lymph node metastasis was 0.7% for actual m-cancer and 20.2% for actual sm-cancer, and it was 1.3% for expected m-cancer and 19.3% for expected sm-cancer. Estimation of the depth of invasion in early gastric cancer using this discriminant function is as accurate as the conventional method. In addition, it could be useful for predicting lymph node metastasis.
Key words
estimation of invasion depth, early gastric cancer, depth of invasion of early gastric cancer, discriminant analysis, multivariate analysis
Jpn J Gastroenterol Surg 24: 2113-2118, 1991
Reprint requests
Eiji Kanehira The Department of Surgery (1), Kanazawa University School of Medicine
13-1 Takaramachi, Kanazawa, 920 JAPAN
Accepted
April 17, 1991
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