A Clinical Study on Noncurative Surgical Factors in Colorectal Cancer

Takuya Yamamura, Akira Hanai, Hiroshi Oikawa, Keisuke Seo, Osamu Akaishi, Toshiya Senda, Kenji Katayama, Hiromu Watanabe

First Department of Surgery, St. Marianna University School of Medicine

A total of 107 patients with colorectal cancer underwent noncurative operations, including 17 relative noncurative resections, 80 absolute noncurative resections and 10 nonresections. There were 66 (62%) patients with a solitary noncurative factors and 41 (38%) with multiple noncurative factors. The 5-year survival rate was 10% for patients with a solitary noncurative factor and 0% for patients with multiple noncurative factors. The result difference was statistically significant. Among patients with a solitary noncurative factor, the 5-year survival rate was 15% for patients with peritoneal dissemination, 4% for patients with liver metastasis and 0% for patients with N₄ lymphnode metastasis or invasion to an adjacent organ. These rates were not significantly different. Regarding the outcome according to the type of treatment, the 5-year survival rate was 29% for patients with relative noncurative resection and no patient with absolute noncurative resection or nonresection survived more than 5 years. There was a significant difference among these groups. Especially the 5-year survival rate for relative noncurative resection with P₁ and H₁ was good, 29% and 60% respectively. The 1-year survival rate was 53% for patients with absolute noncurative resection with multiple noncurative factors in which one of the factors was resected. This rate was better than that for absolute noncurative resection with multiple noncurative factors in which the factors were not resected, though the difference was not significant. These results suggest that resection of the primary lesions and noncurative factors improves the prognosis for patients with noncurative factors.

Key words
relative non-curative resection of colorectal cancer, absolute non-curative resection of colorectal cancer, non-resection of colorectal cancer

Reprint requests
Takuya Yamamura First Department of Surgery, St. Marianna University School of Medicine
2-16-1, Sugao, Miyamae-ku, Kawasaki, 213 JAPAN

Accepted
May 8, 1991

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