A Case Report of Carcinosarcoma of the Pancreas

Yoshinori Matsubara, Hiroki Kenmizaki, Yoshitake Ikeda, Ritsuo Kiuchi, Mizuhiro Mogi, Isao Tatekawa, Masaki Kitajima*

First Department of Surgery, Kyorin University, School of Medicine
*Department of Surgery, Keio University School of Medicine

In a 51-year-old woman who had persistently large amounts of hematemesis and melena, endoscopic findings revealed extensive bleeding associated with a tumor on the second portion of the duodenum. The biopsy specimen of duodenal mucosa showed leiomyosarcoma. The skin had a yellowish tinge caused by obstructive jaundice which developed gradually. We performed surgical treatment for the patient, although there was invasion to the inferior vena cava and superior mesenteric artery, we managed to perform pancreato-duodenectomy. The postoperative pathological specimen showed carcinosarcoma of the pancreas that consisted of adenocarcinoma originating from the pancreas duct and leiomyosarcoma originating from the interstitial tissue. We experienced a rare case of carcinosarcoma originating from the pancreas head. The patient developed abdominal tumor, hematemesis and jaundice. We report what we call carcinosarcoma, including three cases reported in Japan.

Key words
carcinosarcoma of the pancreas

Reprint requests
Yoshinori Matsubara First Department of Surgery, School of Medicine, Kyorin University
6-20-2 Shinnkawa, Mitaka-shi, 181 JAPAN

Accepted
February 12, 1992

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