A Case of Cholangiocellular Carcinoma Associated with Formation of Induration and Ulceration in Abdominal Wall by Development of Direct Invasion

Kohtaro Matsushita, Fuminori Gohda, Hisao Wakabayashi, Takashi Maeba, Satoshi Tanaka

First Department of Surgery, Kagawa Medical School

A cholangiocellular carcinoma arising in the left lobe of liver in a 64-year-old man remained unresectable because of infiltration to the hepatic duct of the anterior segment of the right lobe. During a period of 6 months after surgery, the tumor invaded the anterior abdominal wall and caused extensive cutaneous induration and ulcer, without demonstrating further progression towards the hepatic hilum or causing obstructive jaundice. Histological examination of the lesion revealed well-differentiated tubular adenocarcinoma. Radiotherapy, hyperthermia and intra-arterial infusion chemotherapy via the bilateral internal thoracic arteries achieved no remarkable effect, the patient died 1 year and 8 months after the surgery. This type of extension of cholangiocellular carcinoma seems to be extremely rare and has seldom been reported in the domestic literature.

Key words
abdominal wall invasion of cholangiocellular carcinoma

Reprint requests
Kohtaro Matsushita First Department of Surgery, Kagawa Medical School
1750-1 Ikenobe Miki-cho, Kita-gun, Kagawa, 761-07 JAPAN

Accepted
May 11, 1993

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