Treatment for Early Colorectal Cancer

Yasumi Araki, Hiroki Iwanaga, Akira Okita, Yutaka Ogata, Tatsuhisa Morodomi, Kazuo Shirouzu, Hiroharu Isomoto, Teruo Kakegawa

First Department of Surgery, Kurume University School of Medicine

The present study was undertaken to define the best treatment policy for early colorectal cancer. The subjects consisted of 157 patients with early colorectal cancer (81 mucosal cancer and 76 submucosal cancer). They were assessed from a surgical standpoint based on preoperative diagnosis of the depth of cancer invasion, the treatment method employed and lymph node metastasis. Preoperatively, the depth of cancer invasion was correctly diagnosed by endoscopic ultrasonography in 76.5% of the patients. The endoscopic ultrasound system was therefore proved to be useful for the preoperative diagnosis of the depth of cancer invasion in early colorectal cancer. The rate of lymph node metastais according to risk factors was depth of cancer invasion in early colorectal cancer. The rate of lymph node metastais according to risk factors was depth of cancer invasion (sm₂ or more) 18.0%, lack of adenomatous components 30.8%, lymphatic permeation positive 39.1%, budding positive 40.9%, and moderately and poor differentiated adenocarcinomas 55.6%. These were suggested to be important factors indicating the risk of lymph node metastasis in early colorectal cancer.

Key words
early colorectal cancer, endoscopic ultrasound, histological change of budding

Reprint requests
Yasumi Araki First Department of Surgery, Kurume University School of Medicine
67 Asahi, Kurume, 830 JAPAN

Accepted
June 14, 1993

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