A Proposal from Molecular Biology to Clinic -Implication for Gastroinetstinal Cancer-

Eiichi Tahara

First Department of Pathology, Hiroshima University School of Medicine

Each of esophageal, gastric and colorectal cancers shares characteristic genetic alterations in oncogenes and tumor suppressor genes. We transferred these molecular data to clinical practice and made a new strategy of molecular diagnosis of gastrointestinal cancer as a routine work which has started at Hiroshima City Medical Association Clinical Laboratory since August this year. We believe that this strategy may contribute not only to the development of powerful diagnosis but also to understanding of patient prognosis or therapeutic approaches.

Key words
gastrointestinal cancer, oncogene, tumor supressor gene, molecular diagnosis

Reprint requests
Eiich Tahara First Department of Pathology, Hiroshima University School of Medicine
1-2-3 Kasumi, Minamiku, Hiroshima, 734 JAPAN

Accepted
November 1, 1993

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