One of Basaloid Carcinoma of the Esophagus

Akira Kawaguchi, Jyunsuke Shibata, Hiroyuki Naito, Yoshihiro Endo, Masashi Kodama

The First Department of Surgery, Shiga University of Medical Science

We experienced a case of early basaloid carcinoma of the esophagus. the tumor was regarded as type O-Ipl in the new endoscopic classification and the histological findings in the biopsy specimen showed poorly differentiated squamous cell carcinoma. The long diameter of the tumor was 4.8 cm. The edge of the tumor was covered with normal epithelium and its surface was irregular, and the basaloid carcinoma cells extended downward to the submucosal layers histologically. Vascular invasion and the expression of epidermal growth factor receptor were observed. Mediastinal lymphnode metastases and liver metastases were found, the patient died 1 year and 2 months after the operation. Basaloid carcinoma of the esophagus is thought to have a high malignant potential; however more cases are required in the future to make the clinical and histopathological features clear.

Key words
esophageal carcinoma, basaloid- (squamous) carcinoma, basal cell carcinoma

Reprint requests
Akira Kawaguchi The First Department of Surgery, Shiga University of Medical Science
Seta Tsukinowacho, Otsu 520-2 JAPAN

Accepted
December 8, 1993

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