CASE REPORT
A Resected Case of Malignant Rhabdoid Tumor of the Pancreas
Kazuhiko Yamagami, Tadao Manabe1), Nobuo Baba, Kayoko Higuchi2), Noboru Asano3)
First Department of Surgery, Faculty of Medicine, Kyoto University
1)First Department of Surgery, Nagoya City University, School of Medicine
2)Central Clinical Laboratories, Kyoto University Hospital
3)Osaka Saiseikai Noe Hospital
We report a case of malignant rhabdoid tumor (MRT) of the pancreatic head. A 62-year-old man was admitted from a tumor of the pancreatic head confirmed with ultrasonography and computed tomography. Findings during operation did not indicate liver metastasis, lymph nodes metastasis, or dissemination, and we performed pancreaticoduodenectomy. Despite the absolute curative operation, the patient died on the 50th postoperative day, with multiple liver metastasis and peritonitis carcinomatosa. In the hematoxylin-eosin stain, the cytoplasm contained eosinophilic hyaline-like globular inclusions and immunochemistry confirmed reactivity to vimentin but no immunoreactivity to keratin. Under electron microscopy, the most striking ultrastructural feature was the presence of cytoplasmic whorls of filaments of intermediate size. The findings above lead us to diagnose pancreatic MRT. MRT has been reported mostly as renal tumors with aggressive clinical behavior in children. However, a small number of histologically similar extrarenal MRT has been previously described. To our knowledge, this is the first case report of pancreatic MRT.
Key words
malignant rhabdoid tumor, pancreas, immunohistochemical study
Jpn J Gastroenterol Surg 28: 2017-2021, 1995
Reprint requests
Kazuhiko Yamagami Department of Surgery, Osaka Saiseikai Noe Hospital
2-2-33 Imafuku Higashi, Johtoku, Osaka, 536 JAPAN
Accepted
June 14, 1995
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