Surgical Treatment for Hepatocellular Carcinoma with Hepatic Vein Involvement

Chifumi Maruyama, Ken Takasaki, Masakazu Yamamoto

Institute of Gastroenterology, Tokyo Women's Medical College

We studied surgical treatment for hepatocellular carcinoma with hepatic vein involvement. The number of surgical cases with hepatic vein involvement (HV group) was 442. The numbers of Vv3, Vv2 and Vvl in Japanese Liver Cancer Group's rule were 3, 13 and 3. Portal vein involvement (67%) and intrahepatic metastasis (73%), were observed in the HV group, a percentage witch was statistically higher than that of the non HV group (p<0.001). There was no statistically difference in age, sex, associated liver cirrhosis, tumor size or recurrence site between ther HV group and the non HV group. The cumulative survival rate 5 years postoperatively (31%) for the HV group was not statistically significantly different from that (49%) for the non HV group. The cumulative survival rate did not differ significantly according to the degree of hepatic vein involvement (Vv1, Vv2, Vv3). Portal vein involvement influenced the cumulative survival rate in the HV group, and 5 the patients, in the 8 patients in the HV group without portal vein involvement have been alive for over 3 years after the operation. It is considered that single hepatic vein involvement is not a prognostic factor.

Key words
hepatocellular carcinoma, hepatic vein involvement

Reprint requests
Chifumi Maruyama Insitute of Gastroenterology, Tokyo Women's Medical College
8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162 JAPAN

Accepted
July 10, 1996

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