A Case of Resection for Simultaneous Double Cancer of Acinar Cell Carcinoma of the Pancreas and Sigmoid Colon Cancer Combined with Nephrotic Syndrome

Hidetaka Yamanaka, Masahiro Suenaga, Yoshikazu Kokuba, Takashi Kurumiya, Masayuki Kusagawa, Tsuyoshi Hatsuno, Singo Tsuda

Department of Surgery, Nagoya Memorial Hospital

A 52-year-old man was admitted to our hospital because of proteinuria. On admission, his urine albumin level was high (5.92 g/day) and his serum albumin level was low (1.9 g/dl). He was diagnosed as having nephrotic syndrome. Abdominal US and CT showed a mass in the pancreas, suggesting a malignant tumor. Additionally, a barium enema study and fiberoptic colonoscopy were performed because of occult blood in the stool, and sigmoid colon carcinoma was diagnosed. We were concerned that simultaneous pancreatoduodenectomy and sigmoidectomy would cause too much damage and have a high risk of post-operative complications, so we performed subtotal distal pancreatectomy and sigmoidectomy and an operative left renal biopsy. Histologicaly, the pancreatic tumor was diagnosed as acinar cell carcinoma and sigmoid colon was diagnosed as early colon carcinoma invading the submucosa without lymph node metastasis. Postoperatively, the patient was followed without any sign of recurrence, but nephrotic syndrome did not dissapear. Nephrotic syndrome combined with a malignant tumor is well known, but our case is rare because no case of combined pancreatic carcinoma and double cancer has been reported up to now.

Key words
nephrotic syndrome, acinar cell carcinoma of the pancreas, sigmoid colon cancer

Reprint requests
Hidetaka Yamanaka Department of Surgery, Nagoya Memorial Hospital
4-305 Hirabari, Tenpaku-ku, Nagoya, 468-0011 JAPAN

Accepted
February 12, 1998

To read the PDF file you will need Abobe Reader installed on your computer.