A Case of Gastrointestinal Stromal Tumor of the Sigmoid Colon

Maki Murakami, Akio Morikawa, Satoshi Iijima, Akira Suzuki and Koichi Miyazawa

Department of Surgery, Showa Inan General Hospital

We report a rare case of gastrointestinal stromal tumor of the colon. A 35-year-old woman admitted with lower abdominal pain under a diagnosis of peritonitis underwent emergency. Laparotomy showed a large tumor of the sigmoid colon had ruptured, necessitating sigmoidectomy. Histopathological findings showed interlacing fascicles of spindle cells with high cellularity. Immunohistochemically, tumor cells were positive for c-kit and CD34 and negative for alpha-smooth muscle actiin and S-100 protein. The pathological diagnosis was malignant gastrointestinal stromal tumor, uncommitted, of the sigmoid colon. The patient is free of tumor reccurence 18 months since surgery.

Key words
gastrointestinal stromal tumor, sigmoid colon, peritonitis

Reprint requests
Maki Murakami First Department of Surgety, Shinshu University School of Medicine 3-1-1 Asahi, Matsumoto, 390-8621 JAPAN

Accepted
July 24, 2002

To read the PDF file you will need Abobe Reader installed on your computer.