A Case of Extramedullary Plasmacytoma of the Ileum

Yoshiaki Maeda, Yuji Sato, Motoi Baba, Mitsugu Yamamoto, Hiroki Shomura, Shigenori Honnma, Masao Kondo, Tomoo Ito*, Satoshi Ohta* and Satoru Todo

Department of Gastroenterological and General Surgery, Hokkaido University School of Medicine
Department of Pathology, Hokkaido University Hospital*

A 34-year-old man seen for recurrent abdominal pain. He was found in colonoscopy and barium enema to have a 6 cm tumor of the ascending colon. Pathological diagnosis was not possible because the biopsy specimen was rather necrotic. Abdominal computed tomography (CT) showed a tumor of the terminal ileum causing intussusception of the ascending colon. After right hemicolectomy, immunohistological labeling showed the tumor to be extramedullary plasmacytoma of the ileum. The man remains well without evidence of recurrence in the 7 months since surgery. Extramedullary plasmacytoma of the ileum is rare, with only 9 cases, including ours, reported in Japan. Extramedullary plasmacytoma is radio- and chemo-sensitive. Ten-year survival is 61-67%. At present, therapy involves complete tumor resection, radiotherapy added in incomplete resection. Chemoradiotherapy should be used in unresectable or recurrent cases.

Key words
plasmacytoma, extramedullary plasmacytoma, ileum

Reprint requests
Yoshiaki Maeda Department of Gastroenterological and General Surgery, Hokkaido University School of Medicine
Kita 15-jou Nishi 7-chome, Kitaku, Sapporo, 060-8638 JAPAN

Accepted
October 19, 2004

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