A Case of Extraluminally growing Gastrointestinal Tumor of the Stomach with Massive Bloody Ascites

Hiromi Tokita, Takaho Watayou, Takashi Okamura, Yasuhiko Hakamada, Takeo Kubouchi, Kenichirou Mori, Tetsunori Yoshimura, Tadao Murayama, Akihiko Tsuchida* and Tatsuya Aoki*

Department of Surgery, Tokyo Metropolitan Ohtsuka Hospital
Third Department of Surgery, Tokyo Medical University*

In February 2004, a 60-year-old man noticing abdominal distension was admitted for difficulty in oral intake. He was found to have an abdominal tumor with massive bloody ascites. Computed tomography showed a mass about 12 cm in diameter in the upper abdomen with massive ascites, which was removed by abdominal puncture. Distal partial gastrectomy was conducted after his general condition improved. Macroscopically, the tumor originated from the greater gastric curvature and was growing extraluminally. Pathologically, the tumor was stained weakly for KIT, but CD34 was negative. The tumor was diagnosed as epithelioid GIST, and a point mutation of PDGFRα was detected in exon 18. After surgery, ascites disappeared and he shows no evidence of recurrence.

Key words
GIST, bloody ascites, PDGFRα

Reprint requests
Hiromi Tokita Third Department of Surgery, Tokyo Medical University
6-7-1 Nishishinjyuku, Shinjyuku-ku, 160-0023 JAPAN

Accepted
March 22, 2006

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