A Resected Case of Adenosquamous Carcinoma of the Pancreas with Extensive Lesions of Carcinoma in Situ

Isamu Kagawa, Koichi Nishiwaki, Yoshiro Matsumoto, Bunsei Nobukawa¹⁾, Koichi Suda¹⁾ and Koji Yoshida²⁾

Department of Surgery, Asada General Hospital
Department of Pathology, Juntendo University¹⁾
Department of Gastrointestinal Medicine, Kawasaki Medical University²⁾

A 68-year-old woman admitted for epigastralgia and jaundice, diagnosed with a 7×6 cm mass in the head of the pancreas and a right hypernephroma, necessitating pylorus- preserving pancreatoduodenectomy and right adrenectomy. Surgical specimens showed adenosquamous carcinoma in the head of the pancreas and cavernous hemangioma in the retroperitoneal space. The mass in the pancreatic head consisted of 60% squamous carcinoma, 20% adenocarcinoma, and 20% mixtures of adeno and squamous carcinoma. Carcinoma in situ was seen in the main tumor and the main and peripheral pancreatic ducts on the resected pancreas. Carcinoma in situ apparently progressed to adenocarcinoma and/or squamous carcinoma. The woman died of metastases to the liver on 4 months after the operation.

Key words
adenosquamous carcinoma of the pancreas, carcinoma in situ, pylorus preserving Pancreaticoduodenectormy

Reprint requests
Isamu Kagawa Department of Surgery, Asada General Hospital
219 Tsunomori-cho, Marugame, 763-8507 JAPAN

Accepted
April 26, 2006

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