A Case of Mucinous Cystadenoma of the Pancreas Developed during Pregnancy and Delivery

Yoshinao Komatsu, Masuo Nonoyama¹⁾, Hiroyuki Sekiguchi¹⁾, Natsuo Suzuki, Koichiro Tagami and Hideo Shibata²⁾

Department of Surgery, Kouseiren Atsumi Hospital
Department of Surgery¹⁾ and Department of Pathology²⁾, Seirei Hospital

A 31-year-old woman complained of a left upper abdominal mass just a month after delivery of her second child. Distal pancreatectomy with splenectomy was performed. Examination of the resected specimen revealed mucinous cystadenoma of the pancreas with ovarian-like stroma. The stromal-cell nuclei immunohistochemically stained positive for both estrogen receptor and progesterone receptor, and some of the nuclei of the epithelial cells stained positive for progesterone receptor. Since the patient had a history of hyperprolactinemia and she had been breastfeeding her infant, it was suggested that the tumor was stimulated by sex hormones or by prolactin and developed during pregnancy and delivery.

Key words
pancreas tumor, pregnancy

Reprint requests
Yoshinao Komatsu Department of Surgery, Kouseiren Atsumi Hospital
1-1 Akaishi, Kanbe-cho, Tahara, 441-3415 JAPAN

Accepted
May 31, 2006

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