A Case of Dedifferentiated Liposarcoma of the Stomach

Kiichiro Mogami, Hitoshi Kotanagi, Toshiya Sawada, Hitoshi Seki, Masaru Sakusabe, Shinichiro Ohuchi and Ken Saito¹⁾

Department of Surgery and Department of Pathology¹⁾, Akita Red Cross Hospital

A 69-year-old woman with marked anemia was found in an upper gastrointestinal tract series, gastrofiberscopy, and abdominal computed tomography to have tumors originating from the upper gastric body and developing both within and outside the stomach. Although no definitive diagnosis was made, we conducted laparotomy, finding a tumor with three parts and one stalk, which we resected with a small part of the stomach. Histologic examination of the resected specimen showed a large mucinous component and a small fibrous component, both containing atypical spindle cells and multinuclear giant cells. These findings suggested malignant fibrous histiocytoma, but fat cells and atypical lipoblasts observed in a small part of the tumor. Yielded a definitive diagnosis of dedifferentiated liposarcoma. Of the 31 cases of gastric liposarcoma in the Japanese and foreign literature, none was dedifferentiated.

Key words
stromal tumor of stomach, liposarcoma, dedifferentiated liposarcoma

Reprint requests
Hitoshi Kotanagi Department of Surgery, Akita Red Cross Hospital
222-1 Naeshirosawa, Kamikitade-Saruta, Akita, 010-1495 JAPAN

Accepted
October 25, 2006

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