A Case of Liver Metastasis with Fever Early and Twice Developing after Curative Resection for Transverse Colon Cancer

Yoshikazu Yagi, Kenji Ichikawa, Kiyotsugu Takahashi and Naoto Okuda

Department of Surgery, Biyo Public Hospital

A 53-year-old man admitted for epigastralgia, anorexia, and high fever and undergoing right hemicolectomy based on a diagnosis of transverse colon cancer was found in histological examination to have poorly differentiated stageII colon adenocarcinoma. Fever appeared 2 months surgery and abdominal computed tomography (CT) showed a low-density mass 2.5 cm in diameter in the posterior hepatic segment. Following treatment for a liver abscess, the mass grew after 1 month and was diagnosed by liver biopsy as liver metastasis from the colon cancer. After right hepatic lobectomy, fever reappeared 1.5 months later. Abdominal CT showed a low-density mass 2.5 cm in diameter in the residual liver, suggesting recurrent liver metastasis. We started 3 courses of chemotherapy with l-LV/5-FU (RPMI regimen), after which abdominal CT showed a complete response. The patient remains recurrence-free at this writing 3 years and 4 months after chemotherapy ended.

Key words
colon cancer, fever, early recurrence

Reprint requests
Yoshikazu Yagi Department of Surgery, Biyo Public Hospital
148 Yamanoura, Jimokuji, Jimokuji-cho, Ama-gun, 490-1111 JAPAN

Accepted
March 28, 2007

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