A Case of Mucin-Producing Cholangiocarcinoma arising from the Right Hepatic Duct

Atsushi Suzuki, Shohachi Suzuki, Takanori Sakaguchi, Kazuhiko Fukumoto, Shigeyasu Ota, Keisuke Inaba, Yasuo Takehara¹⁾, Satoshi Baba²⁾, Masataka Kikuyama³⁾ and Hiroyuki Konno

Second Department of Surgery, Department of Radiology¹⁾ and Department of Pathology²⁾, Hamamatsu University School of Medicine
Department of Gastroenterology, Hamamatsu Rosai Hospital³⁾

Mucin-producing cholangiocarcinoma is a rare disorder with biliary tract dilation and clinical symptoms related to hypersecreted mucin. We report a case of mucin-producing cholangiocarcinoma arising from the right hepatic duct. A 77-year-old man undergoing abdominal CT for abdominal pain in October 2005 was fouond to have a multilocular cystic mass at the right hepatic duct with dilation of the intrahepatic bile duct and the choledochus, and a swollen gallbladder. ERCP showed an amorphous filling defect in the choledochus without visualization of the right hepatic duct. Peroral cholangioscopy showed excessive mucin secretion in the choledochus with a papillary protrusion in the right hepatic duct. Under a diagnosis of a mucin-producing neoplasm arising from the right hepatic duct, the man underwent extended right hepatic lobectomy, excision of the extrahepatic bile duct, lymphadenectomy, and biliary reconstruction following PTPE in January 2006. The lesion in the right hepatic duct was histologically diagnosed as intraductal papillary mucinous carcinoma without hepatic infiltration or lymph node metastasis. The man remains alive without recurrence 18 months after surgery.

Key words
mucin-producing cholangiocarcinoma, intraductal papillary mucinous neoplasm of biliary tract, hepatectomy

Reprint requests
Atsushi Suzuki Second Department of Surgery, Hamamatsu University School of Medicine
1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192 JAPAN

Accepted
July 25, 2007

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