A Case of Solitary Splenic Metastasis from Ovarian Cancer Resected by Laparoscopic Partial Splenectomy

Naruji Kugimiya, Ryuichiro Suto, Yoshikazu Kaneda, Syungo Miyamoto, Nobuya Zenpo, Satoru Kurata, Kiyoshi Nakayasu and Toshiaki Kamei*

Department of Surgery and Department of Pathology*, Yamaguchi Grand Medical Center

We report a case of solitary splenic metastasis from ovarian cancer that was resected in laparoscopic partial splenectomy. A 65-year-old woman undergoing surgery to remove ovarian carcinoma (stage IIIc) and postoperative chemotherapy in June, 2002. In May, 2006, extremely high (108.6 U/ml) of carbohydrate antigen 125 was found. Abdominal enhanced computed tomography showed a solitary tumor, 20 mm in the spleen with enhanced high density. We suspected solitary splenic metastasis from the ovarian cancer and conducted partial splenectomy in laparoscopic surgery. The surgery took 146 mintes, and intraoperative blood loss was 30 g. Macroscopically, the cut surface of the resected tumor showed a whitish-yellow solid pattern with a clearly 35×25×25 mm border. It was diagnosed pathological by as metastatic poorly differentiated adenocarcinoma from ovarian cancer. The woman is doing well after surgery, being discharged on postoperative days 4 and undergoing adjuvant chemotherapy. We have found no recurrence in the 8 months since surgery. Solitary splenic metastasis is extremely rare and it has been reported that a good prognosis may be achieved by chemotherapy after splenectomy.

Key words
ovarian cancer, solitary splenic metastasis, laparoscopic partial splenectomy

Reprint requests
Naruji Kugimiya Department of Surgery, Yamaguchi General Medical Center
77 Osaki, Hohu, Yamaguchi, 747-8511 JAPAN

Accepted
June 27, 2007

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