A Case of Resected Mucosa-Associated Lymphoid Tissue Lymphoma of the Liver

Takaaki Ito, Kiyoshi Hiramatsu, Yuuichi Machiki, Takashi Akagawa, Taishi Miyata, Akihiro Hirata, Tomohiro Hara, Katsue Yoshida* and Kenji Kato

Department of Surgery and Department of Pathology*, Kiryu Kosei General Hospital

We report a rare case of low-grade marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) occurring in the liver. A 71-year-old-man seen for a space-occupying 0.8 cm lesion of the liver on ultrasound sonography (US) examination was found in needle biopsy to have low-grade marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type. He was not treated in two years and ten months, and the tumor grew to 7.4 cm necessitating hospitalization in February 2006. Laboratory data was within the normal range. Ultrasonography indicated a solitary hypoechoic mass in the posterior segment (S6) of the hepatic right lobe penetrating the portal vein. Computed tomography (CT) revealed a homogenous low-density area not enhanced by dynamic study. The patient underwent partial resection of the liver in March 2006, completely resecting the tumor. The resected specimen showed that atypical small to intermediate lymphoid cells proliferating in the tumor, with lymphoepithelial lesions recognized. The diagnosis was low-grade hepatic marginal zone B-cell MALT lymphoma. The patient has shown no reccurrence in follow-up during the one year since surgical resection.

Key words
hepatic MALT lymphoma, hepatic lymphoma, MALT lymphoma

Reprint requests
Takaaki Ito Department of Surgery, Kiryu Kosei General Hospital
6-3 Orihime-cho, Kiryu, 376-0024 JAPAN

Accepted
March 26, 2008

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