Evaluation of Operative Morbidity by Common Terminology Criteria for Adverse Events v3.0 for Gastric Cancer

Yutaka Kimura, Hiroshi Yano, Takashi Iwazawa, Susumu Miyazaki, Ken Shiozaki, Toshiyuki Kanoh, Tadashi Ohnishi, Takeshi Tono, Yoshiaki Nakano and Takushi Monden

Department of Surgery, NTT West Osaka Hospital

Background: We clarified the benefits and diszdvantages of the evaluating of surgical morbidity using common terminology criteria for adverse events, version 3.0 (CTCAEv3.0), for gastric cancer. Patients and methods: Subjects were 154 patients who had undergone surgery for gastric cancer from December 2004 to December 2006. Surgery involved distal gastrectomy in 93, total gastrectomy in 38, gastrojejunostomy in 10, and others in 13. We prospectively evaluated operative morbidity using CTCAEv3.0. Results: Surgical complications occurred in 125 patients (81.2%), and adverse reactions exceeding grade 3 in 27 (17.5%). Intraoperative complications occurred in 1.3%, surgery-related complications during hospitalization in 19.5%, nonsurgery-related complications during hospitalization in 78.6%, and complications after discharge in 11.7%. There was no hospital death. Median duration of postoperative hospital saty was 21 days. Conclusion: While we conclude that surgical morbidity can be evaluated using CTCAEv3.0 for gastric cancer, further assessment will be necessary to use it practically.

Key words
gastric cancer, surgical morbidity, common terminology criteria for adverse events (CTCAE)

Reprint requests
Yutaka Kimura Department of Surgery, NTT West Osaka Hospital
2-6-40 Karasugatuji, Tennojiku, Osaka, 543-8922 JAPAN

Accepted
June 18, 2008

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