A Case of Indeterminate Mucin-producing Cystic Neoplasm of the Pancreas

Kinuko Nagayoshi, Kazuyoshi Nishihara, Hirotaka Kuga, Hiroaki Matsunaga, Yuji Abe, Toru Nakano, Shoshu Mitsuyama, Minoru Ono¹⁾, Satoshi Toyoshima²⁾ and Syozo Iwamoto³⁾

Department of Surgery, Department of Radiology¹⁾ and Department of Pathology²⁾, Kitakyusyu Minicipal Medical Center
Iwamoto Clinic³⁾

A 68-year-old woman with dysphasia and found to have a multilocular cystic mass in the pancreatic body and tail was found in abdominal ultrasonography and computed tomography to have an 8 cm diameter mass in the pancreatic tail. ERCP showed the main pancreatic duct to be obstructed at the tail and no continuity to be found between the tumor and the pancreatic duct. Distal pancreatectomy, proximal gastrectomy, and splenectomy were done. The mucous-containing cystic tumor found in the pancreas body and tail consisted histopathologically of atypical columnar cells and a fibrous capsule, and had invaded the stomach. No ovarian-type stroma were detected by HE staining or immunohistological examination using estrogen receptor and progesterone receptor antibodies. Adenomatous papillary growth was found in the main tumor and branch pancreatic ducts in the pancreatic margin. Due to the absence of communication between the tumor and the pancreatic duct, we diagnosed this case as an indeterminate mucin-producing cystic neoplasm.

Key words
indeterminate mucin-producing cystic neoplasm, pancreatic neoplasm, intraductal papillary-mucinous neoplasm

Reprint requests
Kinuko Nagayoshi Department of Surgery, Shin-Kokura Hospital
1-3-1 Kanada, Kokurakita-ku, Kitakyusyu, 803-8505 JAPAN

Accepted
July 23, 2008

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