A Case of Localized Peritoneal Malignant Mesothelioma with Lymph Nodes Metastases

Daisuke Inagaki, Kiyofumi Katayama, Ryuji Shiraishi, Hiroyasu Tanabe and Kazuyuki Tani

Department of Surgery, Hiratsuka Kyosai Hospital

We report a case of localized peritoneal malignant mesothelioma with lymph node metastases and recurrence in the abdominal cavity. A 63-year-old woman exposed to asbestos in the workplace and seen for anorexia and weight loss was found in abdominal CT to have a well-defined tumor adhering to the gastric wall. The prospective diagnosis was gastrointestinal stromal tumor of the stomach, necessitating open-laparotomy resection. An elastic soft 10 cm tumor with central necrosis was resected with part of the stomach and satellite lymph nodes. Histopathological and immunohistochemical examination showed the localized tumor to be peritoneal malignant mesothelioma with lymph node metastases. The postoperative course was uneventful, but the tumor recurrenced diffusely in the abdominal cavity 6 months after surgery. Despite chemotherapy with paclitaxel, the woman died 13 months after surgery. Resectable localized peritoneal malignant mesotheliomas are often reported to have a good prognosis, but recurrence may have a dismal outcome.

Key words
peritoneal malignant mesothelioma, localized, lymph node metastasis

Reprint requests
Daisuke Inagaki Department of Surgery, Hiratsuka Kyosai Hospital
9-11 Oiwake, Hiratsuka, 254-8502 JAPAN

Accepted
July 23, 2008

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