A Case of Multiple Gastrointestinal Metastases of Malignant Pleural Mesothelioma

Tomoyuki Monma, Takeshi Sakuma, Mutsuo Yamada, Naoto Katagata, Fumiaki Watanabe, Tadashi Nomizu, Yoshiko Yamaguchi¹⁾ and Seiichi Takenoshita²⁾

Department of Surgery and Department of Pathology¹⁾, Hoshi General Hospital
Department of Surgery II, Fukushima Medical University²⁾

We report a rare case of multiple malignant pleural mesothelioma metastases to the gastrointestinal tract. A 53-year-old man with anemia had undergone surgical resection of the left chest wall for osteosarcoma 18 months earlier. Gastrointestinal endoscopy showed multiple submucosal tumors and biopsy specimens showed metastatic malignant tumors. We conducted laparotomy for hemostasis, and found multiple tumors in the small intestine. Immunohistochemical examination showed that tumor cells of specimens from the small intestine stained positive for mesothelial markers, calretinin, and WT1, so we conducted immunohistochemical examination for biopsy specimens of the chest wall and stomach and found positive staining for mesothelial markers. The definitive diagnosis was multiple gastrointestinal metastases of malignant pleural mesothelioma.

Key words
malignant pleural mesothelioma, gastrointestinal metastasis, small-bowel metastasis

Reprint requests
Tomoyuki Monma Department of Surgery, Hoshi General Hospital
2-1-16 Omachi, Koriyama, 963-8501 JAPAN

Accepted
December 17, 2008

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