A Case Report of Localized Gastric AL-Type Amyloidosis with a Stricture of the Pylorus

Masakazu Harada, Yasue Iwatani, Motonori Nakagawa, Yuji Toh, Takaaki Nagae, Toshihiro Noake and Yasumi Araki

Department of Surgery, Kurume Coloproctology Center

We report a case of localized AL gastric amyloidosis. A 55-year-old man with nausea and vomiting was find in radiological examination to have pyloric stenosis and gastric expansion, but no mucosal, tumoral, or ulcerative gastric changes suggestive of malignancy endoscopically and the endoscope was easily inserted into the duodenum. Antrum, body, and duodenum biopsy showed normal findings. Abdominal computed tomography (CT) showed wall thickening in part of the stomach. Distal gastrectomy involving gastric wall thickening was performed because malignancy could not be denied. Microscopic examination of the resected specimen showed an AL amyloid deposit, but no other organs were affected. No findings of amyloid deposits in the rectum, colon, ileum, or jejunum specimens were found, yielding a definitive diagnosis of localized gastric amyloidosis. According to our review, localized gastric amyloidosis has been reported in only 19 cases in Japan.

Key words
localized gastric amyloidosis

Reprint requests
Masakazu Harada Department of Surgery, Kurume Coloproctology Center
2-2-18 Shin-Aikawa, Kurume, 839-0865 JAPAN

Accepted
May 27, 2009

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