A Long Survival Case of Endocrine Cell Carcinoma of the Cecum

Kaoru Takeshima, Kazuo Yamafuji, Atunori Asami, Noritaka Hayashi, Hideo Baba, Nobuhiko Okamoto, Hutoshi Oikawa and Junichi Matsui

Department of Surgery, Saitama City Hospital

We report the long-term survival in a case of endocrine cell carcinoma of the cecum. A 45-year-old man was admitted for an abdominal mass in the ileocecal region and closer examination showed a submucosal tumor of the cecum. In March 1998, right hemicolectomy was done and endocrine cell carcinoma was diagnosed by histological examination. On December 1998, abdominal paraaortic lymph node metastases were found in CT and PE and CVA chemotherapy were conducted. The evaluation was PR in December 1999 and NC in August 2000. CT showed adrenal and paracommon hepatic artery lymph node metastases in March 2001 and pararenal artery lymph node metastases in September 2001. Radiation therapy was done for metastases and both evaluations were PR. A liver metastasis was detected in February 2002, for which CDDP and CPT-11 chemotherapy was done and which subsequently disappeared. In September 2002, weakness in the lower limb muscles occurred and MRI showed spinal cord metastasis on the thoracic level necessitating laminectomy. Lower limb paresis was complete in February 2003, and palliative care was begun. He died in October 2003, 67 months form initial surgery. This case suggested that multidisciplinary treatment including chemotherapy and radiation is effective at least short-term in those with endocrine cell carcinoma of the colon.

Key words
endocrine cell carcinoma, cecum, multidisciplinary treatment

Reprint requests
Kaoru Takeshima Department of Surgery, Saitama City Hospital
2460 Mimuro, Midori-ku, Saitama, 336-8522 JAPAN

Accepted
January 31, 2007

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