Intrahepatic Stones Associated with Cholangiocarcinoma

Tsukasa Tsunoda

The Second Department of Surgery, Nagasaki University School of Medicine

Ninety patients with intrahepatic stones (IHS) associated with cholangiocarcinoma (CC) reported in the literature, including our 17 cases, were analyzed. 1. IHS with CC were more frequently seen in male patients. 2. A long history of cholangitis (more than 20 years) was observed in 36% of cases. 3. Correct preoperative diagnosis of the associated CC was made in only 31 of 75 patients ( 4l%). 4. The main location of CC was the left lobe of the liver. 5. CC existed in contact with stones in almost all patients. 6. Hepatic lobectomy or segmentectomy was done in 42 patients. 7. Cumulative 1, 3 and 5 year survival rates in 75 patiens who received surgery were 29%, 8.6% and 8.6%, respectively. Long-standing cholangitis may promote the occurrence of CC. Therefore, bile stagnation should be completely removed as early as possible by proper drainage procedures and/or hepatectomy in treating IHS.

Key words
intrahepatic stones, cholangiocarcinoma, intrahepatic stones with cholangiocarcinoma

Reprint requests
Tsukasa Tsunoda The Second Department of Surgery, Nagasaki University School of Medicine 7-1 Sakamoto, Nagasaki, 852 JAPAN

Accepted
October 11, 1989

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