A Case of 4 Synchronous Multiple Carcinomas of the Large Intestine after Resection of Carcinomas of the Uterine Body and the Ovary

Katsushi Yada, Kousuke Hayashi, Toshihiko Aki, Junichi Takahashi, Tetsuo Kawamura, Hiroyasu Ogawa, Shinichi Nagamine, Kazuya Azuma, Tadashi Takeuchi

Department of Surgery, Sumitomo Hospital

We experienced a case of 4 synchronous multiple carcinomas of the large intestine after resection ofcarcinomas of the uterine body and the ovary. A 27-year-old female was admitted to our hospital complaining of melena and constipation. She had a past history of bilateral oophorectomy and hysterectomy with lymph node dissection at age20. Barium enema examination revealed ascending colon and sigmoid colon carcinomas and rectal polyps. At the operation, two polyps were found at the rectum and one of them was of doubtful malignancy. Therefore, we performed a right hemicolectomy, sigmoidectomy and amputation of the rectum with lymph node dissection. The histological findings of the cancers of the ascending colon and the sigmoid colon were well differentiated adenocarcinoma and mucinous carcinoma respectively and both of the rectal polyps were moderately differentiated adenocarcinoma. Although we could not clarify the hereditary background of her cancer, our case was thought to be very intersting because it has much in common with the cancer family syndrome.

Key words
multiple carcinomas of the large intestine, multiple primary carcinomas, cancer family syndrome

Reprint requests
Katsushi Yada The First Department of Surgery, Osaka City University Medical School
1-5-7 Asahi-machi, Abeno-ku, Osaka, 545 JAPAN

Accepted
November 8, 1989

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