A Case of Primary Gastric T-cell Lymphoma with Helper/Inducer Phenotype

Yasushi Shiraishi, Satoshi Tanaka, Takashi Maeba, Shinya Yamamoto

First Department of Surgery, Kagawa Medical School

A case of T-cell primary gastric malignant lymphoma in a 61-year-old male is reported. The tumor occupied a large part of the body and antrum of the stomach with direct invasion into the pancreas and multiple lymph node metastases around the abdominal aorta and the roots of the celiac and superior mesenteric arteries. Immunohistochemical analysis of the membrane antigen of the tumor lymphocytes for subunit classification revealed phenotypical correspondence with helper/inducer T cells. Most primary gastric malignant lymphomas have been reported to be of B-cell origin, and according to the literature this will be the fifth case of such a lymphoma of T-cell origin ever reported in this country. Total gastrectomy was performed and was followed by chemotherapy with a combination of vincristin, cyclophosphamide, adriamycin and prednisolone, and this has been so effecitve that the residual intraabdominal mass disappeared from the CT-scan 10 months after the initiation of thepapy.

Key words
T-cell lymphoma, gastric malignant lymphoma, immunohistochemical analysis

Reprint requests
Yasushi Shiraishi First Department of Surgery, Kagawa Medical School
1750-1 Ikenobe, Miki-cho, Kida-gun, Kagawa, 761-02 JAPAN

Accepted
March 7, 1990

To read the PDF file you will need Abobe Reader installed on your computer.