Two Cases of Renal Cell Carcinoma Metastasized to the Pancreas and to the Gallbladder

Masanori Terashima, Hikomitsu Abe, Kazunori Suga*, Fumio Matsuya**, Kentaroh Kobayash**, Susumu Itoh**, Ryokoh Sasaki¹⁾, Senji Kanno¹⁾, Kazuyoshi Saito¹⁾, Nobukazu Tomichi²⁾

Department of Surgery, Kazuno Kumiai General Hospital
Departmen of Urology, Kazuno Kumiai General Hospital^*
Department of Medicine, Kazuno Kumial Genral Hospital^**
First Department of Surgery, Iwate Medical Univerisity¹
First Department of Pathology, Iwate Medical University²

We report two cases of renal cellcarcinoma meatastasized to the pancreas and to the gallbladder. Case 1: A 65-year-old female patient, who underwent radical right nephrectomy for renal cell carcinoma 7 years ago, was admitted to our hospital suffering from back pain. On physical and laboratory examination, there were no significant findings except for a diabetic pattern in the glucose tolerance test. Enhanced CT and angiography revealed a relatively well-defined mass at the tail and body of pancreas. Sixty of pancreatectomy with splenectomy was performed. Histological examination revealed pancreatic recurrence of clear cell type renal cell carcinoma. Case 2: A 61-year-old male patient was admitted with the complaint of constipation. There were no abnormal physiological findings. Blood chemistry on admission showed a slight increase in total bilirubin (1.2 mg/dl). Endoscopic retrograde cholangiopancreatography revealed a tumor at the fundus of the gallbladder. Angiogram revealed a hypervascular tumor at the fundus of the gallbladder and the upper pole of the right kidney. Right radical nephrectomy and extended cholecystectomy were performed. Histological examination revealed renal cell carcinoma of the right kidney with a metastatic tumor of the gallbladder.

Key words
renal cell carcinoma, metastasis to the pancreas and gallbladder

Reprint requests
Masanori Terashima First Department of Surgery, Iwate Medical University
19-1 Uchimaru, Morioka, 020 JAPAN

Accepted
February 14, 1990

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