Surgical Treatment and Post-operative Adjuvant Chemotherapy in Gastric Maliganant Lymphoma

Masatsugu Kitamura, Kuniyoshi Arai, Kaoru Miyashita, Goro Kosaki, Tazuko Ibuka*

Department of Surgery, Department of Chemotherapy*, Tokyo Metropolitan Komagome Hospital

Twenty seven patients with malignant lymphoma of the stomach treated at our surgical department were divided into two groups, a curative resection group (20 cases) and a non-curative resection group (7 cases). The result of their surgical treatment and the chemotherapeutic schedule for these types of malignancies were studied. Although the five-year survival rate for the curatie resection group was relatively favorable at 78.4%, that of the non-curative resection group was poor at 35.7%. In curative cases, the relationship between the presence or absence of lymph node involvement and the survival rate revealed no significant difference in the five-year survival rate. The five year survival rate for ten lymph node positive patients was 89.5% and that for seven lymph node negative patients was 84.6%, except that three patients died of other diseases. Two of the five patients with extensive invasion to surrounding organs (S₃-cases) survived ten or more years after extensive resection. As in the patients with gastric cancer, these results show that a good result can be obtained through a curative resection with adequate lymph node dissection or through lymph node dissection combine with resection of the invaded organs. The optimal post-operative chemotherapy as one of the multidisciplinary therapies was also an important factor in improving the prognosis of gastric malignant lymphoma.

Key words
gastric malignant lymphoma, surgical lymph node dissection, adjuvant chemotherapy, prognosis of gastric malignant lymphoma

Reprint requests
Masatsugu Kitamura Department of Surgery, Tokyo Metropolitan Komagome Hosptial
3-18-22 Honkomagome, Bunkyo-ku, Tokyo, 113 JAPAN

Accepted
May 9, 1990

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