A Study of the Prognostic Factors of Primary Gastrointestinal Malignant Lymphoma

Takanori Kawaguchi, Yoshiro Oguchi, Nobuo Ogino, Toshimitsu Majima, Akihiro Ochi, Yukio Oshita, Suzuo Kobayashi, Tetsuto Takao

Department of Surgery, Kure National Hospital

The prognostic factors of primary malignant lymphoma of the gastrointestinal (GI) tract were analyzed in 17 operated patients with using Naqvi's classification that is mainly based on lymph node involvement and depth of tumor invasion. The group of earlier clinical stages, or stage-I and -II (n=11), had 74.l% of 5 year survival rate, while advanced groups, or stage-III and -IV (n=6), had 33.3% (p<0.05). It is therefore indicated that lymph node involvement more than n₂ and tumor exposure to the serosal surface were probably definitive prognistic factors. The groups of curative and non-curative operation had 80.0% (n=8) and 42.9% (n=9) of 5 year survival, respectively. The groups with and without adjuvant chemotherapy had 74.0% (n=11) and 33.3% (n=6) of 5 year survival, respectively. As indicated above, curability of operation and adjuvant chemotherapy also significantly influenced on the prognosis. The present study suggested that Naqvi's classification is a useful tool to predict the prognosis of the primary malignant lymphoma of the GI tract.

Key words
malignant lymphoma, gastrointestinal malignant lymphoma, prognostic factors

Reprint requests
Tetsuto Takao Department of Surgery, Kure National Hospital
3-1 Aoyama-cho, Kure, 737 JAPAN

Accepted
June 13, 1990

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