Pathophysiology of the Lesion Around the Esopagogastric Junction -With Special Reference to the Electromyogram, Internal Pressure and pH-

Teruo Kouzu, Masayasu Murashima, Minoru Muraoka, Shinichi Miyazaki, Fumiaki Sakaguchi, Etsuo Hishikawa, Miwako Arima, Hajime Tanaka, Hideki Ishijima, Youichi Sakuma, Shoichi Onoda, Tsuyoshi Hirashima, Kaichi Ishono

Second Department of Surgery, Chiba University

Sixty-three patients with an esophagogastric junctional lesion, esecially reflux espagitis, were examined in our instiute by our original methods to analyze the electromyogram, internal pressure and pH simultaneously through an endoscopic guide. When there is some kind of system of monitoring the acidity in the esophageal mucosa, analysis of the electromyogram shows that the washing out function of the esohaus against acid is present not only in the normal esophagus but also even in the case of esophagitis when it is mild type. However, in the case of moderae or severe esohagitis, the function is resumed to be lost. There are many factors which need further investigation in relation to whether the function is reversible or not once it has disappeared. The answer to this argument should give a clear indication regarding surgical treament for reflux esophagitis.

Key words
reflux esophagitis, electromyogram, esophagogastric junction

Reprint requests
Teruo Kouzu Second Department of Surgery, Chiba University
1-8-1 Inohana, Chiba, 280 JAPAN

Accepted
June 13, 1990

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