A Case Report of Adenosquamous Carcinoma of the Liver with Hepatolithiasis

Tetsuya Horiuchi, Masahiro Sakaguchi, Sumikazu Oka, Seiki Yamamoto, Yoshihiro Kamada, Shinji Tanaka, Katsuyoshi Tabuse

Department of Surgery, Osaka-minami National Hospital

We experienced a case of adenosquamous carcinoma of the liver with hepatolithiasis. The patient was a 74-year-old man having epigastralgia and pyrexia as chief complaint, who came to our hospital for suspected hepatolithiasis and choledocolithiasis. Various examinations suggested a complication of hepatolithiasis and hepatic abscess, for which a left lobectomy was performed. Pathohistologically, cholangiocarcinoma and squamous cell carcinoma were found adjacent to the left bile duct and in the lateral superior segment, respectively, leading to the diagnosis of hepatolithiasis complicated by adenosquamous carcinoma of the liver. Liver metastasis occurred 3 months postoperatively, resulting in death from hepatic insufficiency 9 months later. Adenosquamous carcinoma of the liver was reported for the first time by Pianzola et al. in 1971 and has been reported 21 times since then. Although an intrahepatic site of squamous cell carcinoma is still controversial, we believe in the present case that the squamous cell carcinoma originated in cholangiocarcinoma, and the possible involvement of hepatolithiasis in cholangiocarcinoma was also suggested.

Key words
adenosquamous carcinoma of the liver, hepatolithiasis

Reprint requests
Tetsuya Horiuchi Second Department of Surgery, Fukui Medical School
23 Shimoaizuki Matsuoka-cho, Yoshida-gun, Fukui, 910-11 JAPAN

Accepted
November 19, 1990

To read the PDF file you will need Abobe Reader installed on your computer.