CASE REPORT
Clinicopathological Study on 13 Cases of Hepatocellular Carcinoma Presenting Extrahepatic Growth
Keitaroh Kan, Hiroshi Kohnosu, Masatoshi Ike, Kohichi Shirono, Atsushi Horii, Yoshikazu Shimode, Hayazoh Kubo, Hirosumi Itoi, Teruhisa Sonoyama, Masao Kobayashi, Kazuyo Naitoh, Hisakazu Yamagishi, Takahiro Oka, Takeshi Hironaka1), Kenji Tsukamoto2)
The Second Department of Surgery, Kyoto Prefectural University of Medicine
1) Kohoku General Hospital
2) Akashi Municipal Hospital
We experienced 13 cases of extrahepatically growing hepatocellular carcinoma in our department and assessed the clinicopathological features and prognosis after surgical treatment. Compared with patients with intrahepatically growing hepatocelluler carcinoma, they showed a higher positive rate of hepatitis B surface antigen (5/12 cases, 41.7%), a larger tumor size (7.2 cm in mean diameter), and a higher frequency of portal venous invasion and/or intrahepatic metastasis (9/13 cases, 69.2%). We performed systemic segmentectomy or lobectomy in nine of the 13 cases, and partial hepatectomy in the others. To date only four patients in the performed systemic hepatectomy group have been free from recurrence in the follow-up period of 10 to 57 months after the operation. All the patients in the performed partial hepatectomy group showed recurrence in the residual liver. In consideration of the prognosis and pathological characteristics, systemic segmentectomy or lobectomy should be performed for better prognosis for patients with extrahepatically growing hepatocellular carcinoma.
Key words
hepatocellular carcinoma, extrahepatic growth
Jpn J Gastroenterol Surg 24: 2032-2036, 1991
Reprint requests
Keitaroh Kan Second Department of Surgery, Kyoto Prefectural University of Medicine
465 Kajii-machi, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602 JAPAN
Accepted
March 13, 1991
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