A Case Report of the Chronic Pancreatitis Normalization of Various Tumor Maker after Pancreaticojejunostomy

Kazuihide Ura, Satoshi Tamaki, Toshiaki Shiogama, Teiji Matsumoto, Toshifumi Eto, Tohru Segawa, Koichi Motojima, Tsukasa Tsunoda, Ryoichi Tsuchiya*

Second Department of Surgery, Nagasaki University School of Medicine
*Shimane Medical College

A 52-year-old man was admitted to our department because of chronic alcoholic pancreatitis. His main pancreatic duct was markedly dilated, and many pancreatic stones were detected by CT scanning. Other imaging examinations showed no evidence of pancreatic cancer. However, serological tests revealed that tumor markers, CA19-1, Dupan-2, Elastase-I were elevated, in spite of his Lewis blood type being Le (a-, b-). After side-to-side pancreaticojejunostomy, all the tumor markers except Dupan-2 returned to the normal level. In cases of malignant disease, serum CA19-9 can be elevated even if the red blood cell type is Le (a-, b-). However, there has been no such report on benign diseease.

Key words
carbohydrate antigen 19-9, Lewis blood type, chronic pancreatitis

Reprint requests
Kazuhide Ura The Second Department of Surgery, Nagasaki University School of Medicine
7-1 Sakamoto-machi, Nagasaki, 852 JAPAN

Accepted
May 8, 1991

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