Morbidity of Abdominal Surgery in Patients with Collagen Disease

Nobuya Karimine, Hiroaki Ueo, Tsukasa Asoh*, Shinya Arinaga, Ryoji Abe, Hiroshi Inoue, Daisuke Watanabe, Hideo Matsuoka, Kiyoshi Takamuku, Masaaki Nagamatsu, Tsuyoshi Akiyoshi

Department of Surgery, Medical Institute of Bioregulation, Kyushu University
*Department of Surgery, Yamaga Municipal Hospital

To determine the risk factors in abdominal surgery for patients with collagen disease, the records of 21 patients operated on were analyzed for their clinical features and surgical results. Fourteen patients (66.7%) showed dysfunction of the vital organs due to involvement by collagen disease and 14 patients had been treated with steroids. The patients with a poor outcome (hospital death) had a higher percentage of emergency operations (p<0.05) and operations for collagen disease-related problems, including intestinal perforation and acute pancreatitis (p<0.01) than those with favorable postoperative course. On the other hand, 17 patients with elective surgery for non collagen disease-related lesions, such as gastric cancer and cholelithiasis, had a favorable outcome. We conclude that elective abdominal surgery is generally well tolerated in patients with collagen disease and that early and adequate surgical treatment is especially important in patients exhibiting the symptoms of acute abdomen.

Key words
risk factors in abdominal surgery for patients with collagen disease

Reprint requests
Nobuya Karimine Department of Surgery, Medical Institute of Bioregulation, Kyushu University
4546 Tsurumihara, Beppu, 874 JAPAN

Accepted
September 4, 1991

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