A Case of Toxic Epidermal Necrolysis with Intestinal Lesions

Atsushi Takano, Takuro Ogata, Keijiro Araki, Kimio Matsuura, Akira Kaneko, Ken Yoshikawa

First Department of Surgery, Kochi Medical School

A 42-year-old woman had abdominal pain and abdominal fullness following improvement of the skin lesion of "toxic epidermal necrolysis (TEN)" caused by an antiinflammatory drug. The ileo-cecal region was resected under the diagnosis of mechanical ileus. The resected specimen had a reddish mucosa with multiple erosions and necrotic tissue. Histological examination revealed necrotic changes in the mucosal layer, but the layers below the mucosal muscle remained almost intact. These findings were similar to the pathological changes in the skin lesion of TEN. The intestinal lesion seems to be part of the systemic lesions of TEN.

Key words
intestinal lesion of toxic epidermal necrolysis

Reprint requests
Atsushi Takano Matsudo Hospital
123-1 Takatsukashinden, Matsudo-shi, 271 JAPAN

Accepted
October 9, 1991

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