Clinical Feature of Colorectal Cancer with a Family History

Fumiaki Watanabe, Tadashi Nomizu, Yoshiro Ando, Tsuneyuki Yoshida, Atsuo Tsuchiya, Rikiya Abe

Second Department of Surgery, Fukushima Medical College

Of 224 patients with colorectal cancer who underwent surgical treatment in the Second Department of Surgery, Fukushima Medical College, 14 (6.7%) had a family history of colorectal cancer (group 1), 35 (15.6%) had a family history of other cancer (group 2), and 174 (77.7%) had no family history of cancer (group 3). At the time of diagnosis in group 1, the patients were significantly younger than those in the other groups. Tumors of group 1 patients tended to be located mainly in the colon. The frequency of double cancer was 7.1% in the group 1 which was significantly higher than in group 3. According to these results, the group 1 patients seemed to have almost the same clinical feature as the patients with "familial colorectal cancer". A family history is useful for the early detection of colorectal cancer and seems to be one of the valuable aids for obtaining a good prognosis.

Key words
family history, hereditary non polyposis colorectal cancer

Reprint requests
Fumiaki Watanabe Second Department of Surgery, Fukushima Medical College
1 Hikarigaoka, Fukushima, 960-12 JAPAN

Accepted
February 12, 1992

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