CASE REPORT
A Case of Familial Polyposis Coli Associated with Carcinoma of the Papilla of Vater
Toshihiko Iseki, Kazufumi Kunitomo, Yasutaka Miyoshi, Seigo Yada, Toshinobu Matsumura, Shigeharu Takai, Nobuhiko Komi, Toshiaki Sano*
First Department of Surgery and First Department of Pathology*, School of Medicine, Tokushima University
A case of familial polyposis coli (FPC) associatd with a carcinoma of the papilla of Vater is reported. A sixty-eight-year old woman had undergone a total colectomy because of multiple colon carcinomas due to FPC three years prior to the present history. Gastroduodenoscopy was carried out because of persistent epigastralgia and revealed an ulcerated lesion at the papilla of Vater. Adenocarcinoma of the papilla of Vater was confirmed by endoscopic biopsy. Curative pyloric preserving pancreaticoduodenectomy (PPPD) was carried out. Post operative histopathological investigation revealed a moderately differentiated adenocarcinoma invading the sphincteric muscle. No metastatic lesion was found but an associated adenoma was found in one area. The incidence of development of carcinoma at the papilla of Vater in patients with FPC is reported to be 100-to 200-fold higher than in the general population but only 22 cases including the present case have been reported in Japan.
Key words
familial polyposis coli, carcinoma of the papilla of Vater, pyloric preserving pancreaticoduodenectomy
Jpn J Gastroenterol Surg 25: 1315-1319, 1992
Reprint requests
Toshihiko Iseki First Department of Surgery, School of Medicine, Tokushima University
3-18 Kuramoto-cho, Tokushima, 770 JAPAN
Accepted
February 12, 1992
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