A Clinical Study on Superficial Spreading Type of Gastric Malignant Lymphoma

Tsuyoshi Kito, Yoshitaka Yamamura, Yoshinori Nakamura, Takashi Hirai, Junichi Sakamoto, Kenzo Yasui, Takeshi Morimoto, Tomoyuki Kato, Mitsunori Yasue, Seiichi Miyaishi, Hiroaki Nakazato

Department of Gastroenterological Surgery, Aichi Cancer Center

Results of treatment of malignant lymphoma have been improved by advances in research. Attempts to introduce new treatments of gastric malignant lymphoma, whose incidence has been increasing, have been made in recent years. In this study we investigated the superficial spreading type of gastric malignant lymphoma, about which new knowledge has been obtained. Of 102 patients who underwent gastric resection for gastric malignant lymphoma at gastric resection for gastric malignant lymphoma at Aichi Cancer Center between 1965 and 1990, 26 had the superficial spreading type of gastric malignant lymphoma. Of these 26 patients, 19 had submucosal invasion, 10 had tumors more than 20 cm in maximum diameter, 11 had lymph node metastasis, 12 underwent R₂ lymph node dissection, and 19 underwent total gastrectomy. The 10-year survival rate was 86.8%, and only one patient died to recurrence. It is concluded that the prognosis of gastric malignant lymphoma is good in patients receiving proper gastrectomy with lymph node dissection. The histological classification of 24 cases was MALT lymphoma which is defined by Isaacson et al. RLH which is defined by Nakamura et al. has been considered identical to MALT lymphoma. In conclusion, recognition of the superficial spreading type of gastric malignant lymphoma is important for understanding the entity of gastric malignant lymphoma.

Key words
malignant lymphoma, superficial spreading type of gastric malignant lymphoma, mucosaassociated lymphoid tissue lymphoma, gastric malignant lymphoma

Reprint requests
Tsuyoshi Kito Department of Gastroenterological Surgery, Aichi Cancer Center
1-1 Kanokoden, Chikusa-ku, Nagoya, 464 JAPAN

Accepted
May 13, 1992

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