A Case of Early Gastric Cancer Which was Found by Leser-Trélat Sign

Naoki Imai, Masahiro Sekino, Yukio Shimizu, Ryuji Hosono, Masahiro Goto, Nobuyasu Kano, Hiroshi Tanabe, Nobuo Fukushima*

Department of Surgery, *Department of Dermatology, General Yōrō Central Hospital

A 62-year-old man visited the department of dermatology at our hospital because of itching in February 1991. On his second visit in the following May, small light to dark brown multiple papulae were observed over the back as well as the abdomen. Histopathological study of the skin yielded findings indicative of verruca senilis. With the proliferation of papula over a short period, a diagnosis of Leser-Trélat sign was made, followed by probing for any malignant tumor of the viscera, which disclosed a IIc+IIa-like lesion on the posterior wall of the gastric antrum. The condition was diagnosed as early gastric cancer, and subtotal gastrectomy with regional lymph node excision was performed. Histopathologically, the condition was classified as well differentiated tubular adenocarcinoma, m, n₀, stage I according to The General Rules for the Gastric Cancer Study by the Japanese Research Society for Gastric Cancer. Up to the present, no proliferation of verruca was observed. To date, no etiological association between Leser-Trélat sign and malignant tumors has been confirmed. The present case, however, could have a certain clinical significance from the aspect of early diagnosis and treatment of malignant tumors.

Key words
Leser-Trélar sign, early gastric cancer

Reprint requests
Naoki Imai Department of Surgery, General Yō rō Central Hospital
986 Oshikoshi, Yō rō -cho, Yoro-gun, Gifu, 503-13 JAPAN

Accepted
May 13, 1992

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