Clinicopathological Study of Mucinous Carcinoma of the Colon and Rectum

Naoki Saigusa, Hiromi Sarashina, Norio Saitoh, Masao Nunomura, Hajime Nakayama, Nobuyuki Nakajima

First Department of Surgery, Chiba University Shool of Mdicine

Clinicopathological features of 28 cases of mucinous carcinomas of the large intestine were compared with those of 493 cases of well or moderately differentiated adenocarcinoma as a control. Mucinous carcinoma was more common in males and young people. Mucinous carcinoma had a greater likelihood of location in the right colon, deep invasion through the bowel wall, and lymph node metastasis than the control. Eleven cases of the floating type of mucinous carcinoma showed a greater likelihood of occurrence in young people, location in the rectum, invasive or special type, deep invasion, lymph node metastasis, venous invasion, peritoneal dissemination and poor prognosis than 14 cases of the fixed type. With the HID-AB staining method, 57.1% of the fixed type were the sulfomucin-predominant type and 85.7% of the floating type were the sialomucin-predominant type.

Key words
mucinous carcinoma of the large bowel, high iron diamine-alcian blue stain, mucous module, fixed type and floating type of mucinous carcinoma

Reprint requests
Naoki Saigusa Surgical Department, Kimitsu Chuo Hospital
1010 Sakurai, Kisarazu-shi, 292 JAPAN

Accepted
October 7, 1992

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