INVITED LECTURE
Aggressive Surgical Approaches to Advanced Carcinoma of the Biliary Tract
Masato Nagino, Yuji Nimura, Naokazu Hayakawa, Junichi Kamiya, Satoshi Kondo
First Department of Surgery, Nagoya University School of Medicine
Forty-five patients with far advanced (stage-IV) gallbladder carcinoma and 52 patients with carcinoma of the hepatic hilus who had undergone radical resection were studied. Various hepatic segmentectomies were used in 85 patients (87.6%). Furthermore pancreatoduodenectomy and/or portal vein resection were concomitantly performed in 19 patients (19.6%) and 24 patients (24.7%), respectively. In stage-IV gallbladder carcinoma, the survival time of the patients with peritoneal seeding, liver metastasis, or positive paraaortic nodes was extremely poor (3-year survival rate was 5.6%, 50% survival time was 9.8 months). By contrast, the survival of the patients without seeding, liver metastasis, or positive paraaortic nodes was unexpectedly better (5-year survival rate was 32.8%). In carcinoma of the hepatic hilus, the survival time of the patients with stage-I, -II, and-III was satisfactory (s-year survival rate 43.3%). Although the prognosis for the stage-IV patients was significantly worse (5-year survival rate was 21.5%), there were many long-term survivors among the patients with stage-IV with local staging factors such as hinf, ginf, or vs (+). In conclusion, we believe that aggressive surgery with more adequate indication and further improvement of operative techniques will give a better prognosis for patients with advanced carcinoma of the biliary tract.
Key words
stage-IV carcinoma of the gallbladder, carcinoma of the hepatic hilus, hepatic segmentectomy
Jpn J Gastroenterol Surg 26: 1137-1141, 1993
Reprint requests
Masato Nagino First Department of Surgery, Nagoya University School of Medicine
65 Tsurumai-cho, Showa-ku, Nagoya, 466 JAPAN
Accepted
December 9, 1992
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