A Study Cancer Infiltration at the Resection Margin in Patients with Gastric Cancer who Underwent Non-curative Gastric Resection

Yoshitaka Yamamura, Tsuyoshi Kito, Junichi Sakamoto, Takashi Hirai, Kenzo Yasui, Takeshi Morimoto, Tomoyuki Kato, Mitsunori Yasue, Seiichi Miyaishi, Hiroaki Nakazato

Department of Gastroenterologlcal Surgery, Achi Cancer Center Hospital

The influence of cancer infiltration at the resection margin (infilt (+)) on prognosis for 683 patients who underwent non-curative gastric resection from 1965 to 1984 was studied. The three-year survival rates (3YSR) were evaluated statistically. 3YSR of aw (+) and ow (+) were 40.6% and 36.0%. 3YSR were 32.8% in patients with a single factor of N>R relatively non-curative resection and 10.0% in patients with two factors of N>R relatively noncurative resection plus infilt (+) (p=0.0001). In N>R absolutely non-curative resection, 3YSR of N>R alone was 12.8% and that of N>R plus infilt (+) was 4.8% (not significant, NS). In S₃, 3YSR of S₃ alone and S₃ plus infilt (+) were 28.6% and 0% (NS). 3YSR were 27.8% and 6.3% in patients having the single factor of P₁ and P_2-3 alone, and 21.4% and 0% in patients with the factors of P₁ and P_2-3 plus infilt (+) (NS). 3YSR were 5.7% in patients with more than two non-curative factors alone and 3.4% in patients with more than two factors plus infilt (+). From these results, it was concluded that the prognosis for the patients having positive infiltration at the resected margin was not wrong in those with a large tumor burden.

Key words
cancer infiltration at the resection margin, survival rate of gastric cancer, non-curative gastric resection, non-curative factors of gastric cancer

Reprint requests
Yoshitaka Yamamura Department of Gastroenterological Surgery, Aichi Cancer Center Hospital
1-1 Kanokoden, Chikusa-ku, Nagoya, 464 JAPAN

Accepted
February 10, 1993

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