Pancreatic Acinar Cell Carcinoma in A Young Woman, A Case Report

Takashi Kamiya, Yoshiaki Sugiura, Kimitoshi Inoue, Yutaka Yoshizumi, Shingo Shima, Susumu Tanaka, Seiichi Tamai*

Department of Surgery II, Department of Laboratory Medicine*, National Defense Medical College

A 23-year-old woman underwent pancreatoduodenectomy for pancreatic acinar cell carcinoma in October 1980. As usrgery was absolutely curative, adjuvant chemotherapy was not administered. Chemotherapy with 5-FU, CDDP and OK-432 was started when pulmonary and hepatic metastases were detected in October 1984. Pulmonary metastatic lesions disappeared on an X-ray image five months after chemotherapy, while hepatic metastatic lesions showed minor response. In February 1987, pulmonary metastatic lesions appeared again, however, the second chemotherapy with 5-FU, ADM and MMC failed to show any effect. The lesions were confirmed to be the metastatic lesions of acinar cell carcinoma by open lung biopsy. The patient's condition gradually deteriorated, and she died in January 1987.

Key words
acinar cell carcinoma of the pancreas, chemotherapy for carcinoma of the pancreas, postoperative metastases in the lung and the liver

Reprint requests
Takashi Kamiya Department of Surgery II, National Defense Medical College
3-2 Namiki, Tokorozawa, 359 JAPAN

Accepted
May 11, 1993

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