Risk Factors for Lymph Node Involvement of Early Gastric Cancer -Indications of Endoscopic Resection-

Shingo Yagi, Takuhisa Kawakami, Matsuhei Tanaka, Kouichi Yokoyama, Yasuhiko Tatsuzawa, Hiroyuki Bando, Tetsuji Yamada, Susumu Kitagawa, Masaaki Nakagawa

Department of Surgery, Ishikawa Prefectural Central Hospital

Indications of endoscopic resection therapy for early gastric cancer were obtained by investigating risk factors for lymph node involvement. Of 572 cases of early gastric cancer seen in our hospital from January 1976 to December 1992, node-positive cases numbered 52 (9.1%). Lymphatic and venous invasion, submucosal invasion in depth, diameter in size (>2 cm), and the histological types including moderately differatiated tubular adenocarcinoma (tub 2), poorly differentiated adenocarcinoma (por), and signet-ring cell carcinoma (sig) in histological type were significant risk factors. Stromal type and gross appearance tended to indicate risk. Location of tumor, infiltrative growth and ulceration were not significantly different. We recommend the following indications for endoscopic resection, diameter of less than 2 cm and histological types of papillary (pap) and well differentiated tubular adenocarcinoma (tub 1).

Key words
early gastric cancer, risk factor for lymph node involvement, endoscopic resection

Reprint requests
Shingo Yagi Department of Surgery, Ishikawa Prifectural Central Hospital
Nu-153 Minamishinbo-cho, Kanazawa, 920 JAPAN

Accepted
October 13, 1993

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