A Synchronous Triple Cancer of Hypopharynx, Esophagus and Rectum Treated with Multimodality Therapy

Kazuhiko Hayashi, Hiroko Ide, Reiki Eguchi, Tsutomu Nakamura, Kazunari Yoshida, Ataru Kobayashi, Hidemi Nakamura, Motohumi Tanaka, Yuki Yamashita¹⁾, Yoko Murata, Shigeru Suzuki²⁾, Akiyoshi Yamada³⁾

Department of Surgery¹⁾, Endoscopy²⁾, Radiology³⁾, Institute of Gastroenterology, Tokyo Women's Medical College

The patient was a 67-year-old man who suffered synchronous triple cancer of the esophagus, hypopharynx, and rectum. The esophageal carcinoma was far advanced with aortic and left broncheal invasions. First he was treated with preoperative chemotherapy with CDDP (70 mg/m²; day 1), 5-FU (700 mg/m²; days 1-5), and VDS (3 mg/m²; day 1). After two cycles of chemotherapy he achieved PR in all lesions. The operation was divided into palliative resection of the hypopharyngeal and rectal carcinomas and curative esophagectomy. Post-operative irradiation was given to the hypopharynx, cervix, and upper mediastinum. He has been alive for 11 months with no evidence of recurrence, and has had good quality of life following this successfull multimodality treatment.

Key words
esophageal cancer, synchronous cancer, triple cancer

Reprint requests
Kazuhiko Hayashi Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical Colelge
8-l Kawada-cho, Shinjuku-ku, Tokyo, 162 JAPAN

Accepted
September 8, 1993

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